Why Mesothelioma Cases Occur in St. Louis
St. Louis occupies a unique position in America's industrial history — a city where aerospace manufacturing, nuclear weapons production, chemical processing, and heavy industry converged to create one of the Midwest's most significant asbestos exposure corridors. For much of the 20th century, St. Louis was home to major employers whose operations depended heavily on asbestos-containing materials, and tens of thousands of workers were exposed without any warning about the deadly consequences.
According to WikiMesothelioma.com, the St. Louis metropolitan area has a documented pattern of elevated mesothelioma incidence linked to its aerospace, chemical, and manufacturing industries. The concentration of asbestos-using employers in the region means that many workers accumulated exposure from multiple job sites over the course of careers spanning decades.
The McDonnell Douglas Corporation (now Boeing) operated one of America's largest aerospace manufacturing complexes in St. Louis, employing tens of thousands of workers who built military and commercial aircraft in facilities where asbestos was used in insulation, brake linings, heat shields, and building materials. At the same time, Mallinckrodt Chemical Works processed uranium for the Manhattan Project and the Cold War nuclear weapons program in a downtown St. Louis facility insulated with asbestos throughout. Monsanto, headquartered in Creve Coeur, operated chemical plants where asbestos-containing equipment was standard. Anheuser-Busch, the nation's largest brewer, used asbestos insulation in its brewing equipment and power systems. Laclede Gas and Union Electric (now Ameren) maintained gas distribution and power generation facilities insulated with asbestos materials throughout the St. Louis area.
The 20-to-50-Year Latency Period
Mesothelioma does not appear immediately after asbestos exposure. The disease has a latency period of 20 to 50 years, meaning workers exposed at McDonnell Douglas, Mallinckrodt, or other St. Louis facilities during the 1950s, 1960s, and 1970s are being diagnosed now. An assembler who worked on the F-15 Eagle production line in 1975 may only receive a mesothelioma diagnosis in 2025 or later. This long latency period is why St. Louis continues to produce new mesothelioma cases decades after asbestos use was curtailed.
The diversity of St. Louis's industrial base means that many workers accumulated asbestos exposure from multiple employers. A machinist might have worked at McDonnell Douglas for 15 years, then moved to a maintenance position at a Laclede Gas facility for another decade — each employment adding to the cumulative asbestos burden. This multi-employer exposure history is critical for legal claims because it can connect a patient to multiple asbestos trust funds and multiple defendants, increasing total available compensation.
St. Louis's Asbestos Legacy by the Numbers
The St. Louis metropolitan area was home to hundreds of industrial facilities that used asbestos-containing materials. During peak operations, McDonnell Douglas alone employed over 40,000 workers in St. Louis County. Mallinckrodt processed over 50,000 tons of uranium using asbestos-insulated equipment. Missouri consistently records significant mesothelioma mortality, and the St. Louis region is a primary contributor. If you worked at any major industrial facility in the St. Louis area, documenting your asbestos exposure history is a critical first step toward understanding your legal options.