Skip to main content

finding a surgeon who actually knows multimodal therapy for peritoneal meso

Patient · · 66 views
So I'm about 6 weeks out from diagnosis and I'm trying to figure out how to vet surgeons for HIPEC combined with chemo and whatever else makes sense. I've read that multimodal is the standard of care now but I don't know how to tell if someone actually does this routinely versus just says they do.

I worked at Johns-Manville in Cleveland from 1978 to 1985 on the insulation line and got exposed pretty heavily, so I'm not new to understanding asbestos stuff, but the surgical side is completely foreign to me. My oncologist is solid but she's not the one doing surgery.

Here's what I'm trying to figure out. When I call a treatment center, what questions actually matter? Like, do I ask how many HIPEC procedures they've done? Do I ask about their specific protocol for combining surgery with neoadjuvant chemo versus adjuvant? I've been reading some 2023 and 2024 studies on peritoneal cases and it seems like the sequencing and drug choices matter a lot, so I want to know if the surgeon coordinates with the oncology team or if they're kind of doing their own thing.

I'm also trying to understand whether experience with pleural meso translates to peritoneal or if those are almost different specialties. Someone told me to look for someone trained in cytoreductive surgery specifically but I don't even know if that's standard terminology or if it means something else.

My symptom journal from the last three months shows increasing abdominal distension and pain that got worse in October before I got diagnosed in November, so I know I'm stage II and I want to make sure I'm not wasting time picking the wrong place. Has anyone had experience interviewing surgeons or centers and figured out what actually separates the people who know what they're doing from the ones who are just competent?

13 Replies

Veteran
Cytoreductive surgery is the real deal for peritoneal, yeah. Ask them straight up how many HIPEC cases they do a year and if they coordinate the chemo sequencing with their oncology team before surgery, that'll tell you everything you need to know.
Patient
That's really helpful, thanks. So when you say "coordinate the chemo sequencing before surgery" do you mean they literally sit down with the oncology team and plan it out together, or is that more of a standard protocol thing where everyone just follows the same guidelines? I'm trying to figure out if I should be asking to see documentation of that coordination or if I'm overthinking it. The centers I've called so far haven't really given me specifics on their process when I ask about it.
Patient
Yeah man, I'd also ask if they do the HIPEC right there in the OR or if they ship you somewhere else for it, because some places farm that out and that's a red flag IMO. Good catch on the sequencing thing though, that's the tune-up that actually matters.
Patient
That's a really good point about the HIPEC location. I hadn't even thought to ask that but it makes sense that continuity would matter. Did your center do it in-house? I'm also wondering if you've come across any places that were clear about their neoadjuvant versus adjuvant approach upfront, because so far when I call around it feels like I'm getting vague answers about "we customize the protocol" which could mean anything.
Medical Expert Response
What you're doing right now, six weeks out, asking exactly these questions, that takes real clarity of mind and I want you to know it's the right instinct.

The pleural vs. peritoneal distinction matters more than most people realize. They really are almost different subspecialties. A surgeon who does a lot of extrapleural pneumonectomies may have very limited experience with cytoreductive surgery and HIPEC specifically, and yes, cytoreductive surgery is the correct terminology you want to hear back from them without hesitation.

When I've sat with patients going through this vetting process, the question that separated the real specialists from the "we can do that" centers was asking how many HIPEC procedures they completed in the last 12 months, not career total. A center doing 3 or 4 a year is very different from one doing 30+. The National Cancer Institute designated centers tend to have more volume but not always. The Peritoneal Surface Oncology Group International has a directory that's worth pulling up.

The sequencing question you raised about neoadjuvant versus adjuvant chemo is genuinely sophisticated and honestly most coordinators won't be able to answer it on a first call. But if a surgeon's office can't get you a direct conversation with someone who can explain their specific protocol for peritoneal meso... that itself tells you something.

One thing I'd gently suggest is journaling not just symptoms but also how you feel after each of these calls. Six weeks in is a lot to hold emotionally and cognitively at the same time. And if the anxiety around all this starts feeling like too much to manage alone, talking with an oncology social worker or counselor who specializes in this can really help you stay grounded while you make these decisions.
3 found this helpful
Patient
yeah man that's exactly what I'm dealing with too, except mine was pleural so different beast but same headache trying to figure out who actually knows their stuff versus just going through the motions. I'd say ask them straight up how many of these procedures they do a year and if they work with a specific oncology team on the chemo timing, that tells you pretty quick if they're coordinating or just swinging the knife on their own.
Patient
That's helpful, thanks. The part about asking how many procedures a year is something I hadn't thought to phrase that directly. Did your surgeon give you a clear answer on that or did you have to push for it? I'm worried some places will give me a number that sounds impressive but doesn't actually mean they're doing multimodal cases regularly, you know?
Patient
Hey, I gotta be honest with you - pleural's what I got so I'm not gonna pretend I know peritoneal inside and out. But I went through the surgeon vetting thing back in February when I needed my EPP, so maybe some of that translates.

First thing I did was call MD Anderson in Houston and just asked straight up "who on your team does the most cytoreductive surgery for peritoneal cases." The person I talked to actually knew the answer off the top of her head, which told me they see enough of it to know. When a place has to go hunting for that info, that's a yellow flag. Your oncologist probably has relationships with surgeons already, so ask her directly which centers she'd send her own family to for peritoneal HIPEC. Don't make her guess. Make her pick one.

The sequencing question you're asking is the right one. My surgeon at the time talked through with my chemo team about timing, drug interactions, all that. That coordination matters way more than any one person's credentials. When I called places, I asked "walk me through how your surgeon and oncology department communicate during treatment planning" and listened for whether they actually had a system or if it sounded improvised.

Cytoreductive surgery is real terminology, not made up. It means they're trained specifically to debulk tumors aggressively, which is different from general surgical oncology. Not every good surgeon does it routinely. If someone's doing HIPEC, they should know that term and not have to ask what you mean.

How many procedures matters but the number that matters is like 50+, not 5+. I asked my surgeon straight up "how many EPP's have you personally done" and he said 127. That was worth knowing. You're not wasting time asking that.

You're stage II with three months of getting worse, so yeah, move fast but not stupid. Good luck with this.
Patient
That's actually really helpful, thanks. The fact that they knew the answer immediately is a good sign - I hadn't thought of it that way but you're right, it means it's not some rare thing they do once a year. Did MD Anderson end up being where you went, or did you shop around after that initial call? I'm trying to figure out if I should start with the big national centers or if there's someone closer to Cleveland who actually has the volume. My oncologist mentioned a couple places in Ohio but I want to make sure they're not just saying they do multimodal when what they really mean is surgery plus chemo in sequence rather than actual coordinated therapy.
Veteran
Look, I'm pleural not peritoneal so take that into account, but the vetting process was the same headache for me back in June. Here's what actually mattered when we were calling around.

First thing, ask them straight up how many multimodal cases they've done in the last two years. Not total in their career. Last two years. Places that are legit about this will have a number ready. We called MD Anderson and they said 47 in 2024. Called another center and they hemmed and hawed which told us everything.

The surgeon coordination piece you're asking about is real. My surgical team at VAMC Norfolk coordinated with my oncology folks before my pleurectomy in August. They literally sat down together. So when you call, ask if the surgeon meets with oncology before they schedule you. Not after. Before. If they say "oh the oncologist will handle that part" then you probably keep calling.

Cytoreductive surgery is the right term and yeah it matters for peritoneal cases especially. It's the debulking work they do before HIPEC. Different skill set than pleural work honestly. Pleural is one thing but stripping peritoneum and managing visceral surfaces, that's another animal. Ask them if they've done cytoreductive cases specifically, not just "abdominal surgery."

Neoadjuvant versus adjuvant timing... this is where you actually need to see their protocol on paper. Not just what they tell you. Ask for their standard approach in writing. That's a fair ask and legit places will have it documented. We got ours from my surgical team, showed it to a second opinion surgeon at another hospital in September.

You're not wasting time being thorough. You've got stage II which gives you some runway but yeah, don't drag your feet once you pick the right place.
Veteran
Pleural and peritoneal are pretty different animals, I'd focus on someone who specifically does peritoneal cases routinely. Ask them straight up how many HIPEC procedures they've done in the last year and whether they work with a dedicated oncology team on the sequencing, that'll tell you real quick if they're just dabbling or actually running a program.
Family
So Joe's diagnosis was pleural, not peritoneal, but we went through something similar with finding the right surgeon for his cytoreductive approach combined with immunotherapy. I can't speak to the exact same sequencing you're dealing with but the vetting process... yeah, that matters a lot.

When we called around, the thing that actually stuck with me was whether the surgeon could explain HOW they work with the oncology team. Like, we talked to one place in November 2025 where the surgeon's office basically said "we do the surgery and your oncologist handles chemo" and that felt off to me. Then we got on a call with someone else and within five minutes they were talking about tumor burden, what chemo Joe would be on before surgery, what the scan timing looked like. That person knew Joe's case before we even got there because they'd actually reviewed his films with the oncology team. That's the difference.

The HIPEC question is smart. We asked about volume and also about what the actual failure points are. Like, a surgeon who's doing this routinely will tell you not just the numbers but also what they've learned about complications, what imaging they use to plan, whether they have a perfusionist on staff. If someone gets vague about the technical details that's... not great.

On pleural versus peritoneal, I think you're right that it matters. The anatomy is different, the drug delivery is different with HIPEC. Cytoreductive surgery is the right term and it means they're trained specifically in removing tumor from multiple organs and peritoneal surfaces. That's not the same as general oncologic surgery.

Your instinct about protocol sequencing is exactly right. The 2024 studies on peritoneal cases do show timing matters. Ask them point blank: what's your standard approach with neoadjuvant versus adjuvant, and more importantly, why? The answer will tell you if they're following current literature or just doing what they've always done.

You're not wasting time by being careful about this. You caught it at stage II which is actually... you're in a decent spot to be selective about your team.
Patient
That's really helpful to hear, especially about the coordination piece. When you say the surgeon could explain HOW they work with oncology, did they have like a specific protocol they walked you through, or was it more just their general approach? I'm trying to figure out if I should be asking them to literally show me their treatment plan template or if that's something that only comes after I'm officially a patient there. And I'm curious whether Joe's team had him do chemo before surgery or after, since I keep reading conflicting things about timing with peritoneal cases versus pleural.

Share Your Experience

Sign in or create a free account to share your experience.

Discussions in this community are for informational and emotional support purposes only. They do not constitute legal advice, medical advice, or an attorney-client relationship. Always consult a qualified professional for advice specific to your situation. Community Guidelines

Call Now: (800) 400-1805 Free Case Review • Available 24/7