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The Three Types of Mesothelioma: Epithelioid, Sarcomatoid, and Mixed 0:53
Educational Explainer

The Three Types of Mesothelioma: Epithelioid, Sarcomatoid, and Mixed

A mesothelioma specialist explains the three main cell types — epithelioid, sarcomatoid, and biphasic (mixed) — and why about 40% of tumors contain multiple cell types, which can affect treatment decisions and lead to misdiagnosis.

Published April 14, 2026 Duration: 0:53

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Key Points From This Video

  • There are three main cell-type families of mesothelioma: epithelioid, sarcomatoid, and biphasic (mixed).
  • Epithelioid is the most common type and typically responds best to treatment.
  • Sarcomatoid is more aggressive and harder to treat.
  • About 40% of epithelioid tumors actually contain other cell types, which can affect treatment response and lead to misdiagnosis if not detected.

Important Note

This video presents medical information from a mesothelioma specialist for educational purposes. It is not a substitute for personalized medical advice. Every patient's situation is unique — please consult a qualified mesothelioma physician about your specific diagnosis, treatment options, and prognosis.

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Video Transcript

There are many different types of cells in mesothelioma. There are three predominant families, as we call them: the epithelioid type, the sarcomatoid type, and one in the middle which we call mixed — sometimes biphasic — with two types of cells.

Interestingly enough, when we analyze our epithelioid-type mesotheliomas, about 40% of them have other types of cells within their tumor as well, leading to either mistreatment, early recurrence, or misdiagnosis.

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